Solanesol

Solanesol

[Specification]   13%  95% solanesol
[Detection methods]   HPLC
[Botanical Name]  Nicotiana tabacum L.
[The source of the plant]
 Solanesol is the natural substances which widely existed in higher plant mammal and microorganism especially in tobacco leaf, potato leaf and mulberry leaf. The content achieve 0.3-3% in tobacco leaf. the solanesol is an important raw materials to synthesize the pharmaceuticals. It is the nonreplaceable and key intermediates of ubiquinone--- the side chain of the CoQ10 and Vitamin K2.
[Solanesol as tobacco marker]
Solanesol, a 45-carbon, trisesquiterpenoid alcohol found in tobacco leaves and tobacco smoke, has been used as a quantitative marker for tobacco smoke for years. However, solanesol appears to be unreliable as a quantitative marker for tobacco smoke during environmental air sampling because it can be degraded substantially when present as a component of tobacco smoke and by as much as 100% when present as pure solanesol on fortified filters during air sampling. Since there is strong evidence that ozone is the agent responsible for the degradation, solanesol appears to be unreliable as a quantitative marker during indoor air sampling when indoor levels of ozone are greater than about 15 ppb.
[Molecular formula and molecular weight]  C45H74O : 631.07
[Pharmacology function] 
The solanesol is a kind of sesquterpene enol olefinic alcohol. Solanesol is an important pharmaceutical intermediates. Mainly existed in the deadly nightshade such as tobacco leaf, potato and mulberry. Solanesol can counteract the bacteria, diminish inflammation and hemostasis. It also have strong activity of counteracting the cancer. Mainly used for synthesizing the CoQ10 and Vitamin K 2 and potentiator of fighting for the cancer. It is also can be the synthesized raw materials of some antiallergic agent, anti-ulcerative drug and hypolipidemic and anticancer drugs.

 

 

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