Indole-3-carbinol
[ CAS NO. ] 700-06-1
[ Molecular Formula ] C9H9NO
[ Molecular Weight ] 147.17
[ Appearance ] Off-white solid
[ Uses ] pharmaceutical intermediates for the synthesis of anti-cancer food additives.
Functions of Indole-3-carbinol
1) Indole-3-carbinol has been shown to inhibit cancer cells in animal cancer models of the mammary, liver, and lung. It is currently being evaluated in human clinical trials as a potential chemopreventive agent against breast and ovarian cancers.
2) Indole-3-carbinol appears to work by upregulating or modulating certain enzymes that improve the detoxification of various potential carcinogens—although it appears to be the breakdown products that have this effect rather than Indole-3-carbinol itself.
About Indole-3-carbinol
Indole-3-carbinol (I3C) is a secondary metabolite found in cruciferous vegetables such as broccoli, cauliflower, kale, cabbage and brussels sprouts. A secondary metabolite is one not found preformed in vegetables, but formed after an enzyme in the vegetable (myrosinase) is exposed to a phytochemcial in the vegetable (glucobrassicin). This can occur only when vegetable cells are crushed or eaten, and is referred to as enzymatic hydrolysis. I3C, thus formed, is then broken down in the presence of acid (as in the acid environment of the stomach) to various by-products such as diindolylmethane (DIM), which are then absorbed.
[ Storage ]
Store in cool & dry place; Keep away from strong light and high heat.
[ Shelf life ]
24 months when properly stored
[ Package ]
Enterprise standard. Drums or cartons, 25kgs/drum(carton),2.5kg/bag, double vacuum plastic packing (vacuum sealed foil bags) inside.
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