Sildenafil Mesylate
[ Appearance ] White crystalline powder
[ Dry loss weight ] 0.5%max
[ Cauterant residue ] <0.05%
[ Heavy metal ] 10ppm max
[ Specifications ] 1kg/20kg/50kg are available
[ Functions and use ] It is medicine treatment raw material, indicated for the treatment of erectile dysfunction.
[ Property ]
It is the ramification of Sildenafil Citrate, it is white to off-white crystalline powder, odorlessbitter taste, soluble in water and ethanol.
[ Mechanism ] Sildenafil Mesylate, same as Sildenafil is an inhibitor of type 5 -cGMP phosphodiesterase relaxing and smoothing muscle cells of the corpus cavernosum which leads to penile erection. This relaxation may be mediated by nitric oxide via cyclic guanosine monophosphate (cGMP). .
[ Efficacy ] 52% will takes effect 30 minutes after taking, 82% takes effect 1 hour after taking for Sildenafil Mesylate. It has a terminal half-life of 5-12 hours. Its suggested dosage should be 100-150mg, and 120mg is suggested for the orient.
[ Storage ] sealed in room temperature
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