Nonapeptide-1

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[ Synonyms ] Melanostatine-5; Melanostatine
[ Sequence ] Met-Pro-{D-Phe}-Arg-{D-Trp}-Phe-Lys-Pro-Val-NH2
[ CAS NO. ] 158563-45-2
[ Molecular Formula ] C61H87N15O9S
[ Molecular Weight ] 1206.5
[ Appearance ] White Powder
[ Purity ] ≥98%

[ Function ]
1. Block the binding of α-MSH with its receptor MC1R on the cell membrane of melanocyte;
2. By inhibiting MSH (melanostimulating hormone), reducing melanin production and preventing excessive production of melanin;
3. A whitening agent that works on the very initial stage of skin darkening mechanism;
4. Prevent further activation of tyrosinase & thus blocks melanin synthesis for better control over skin tone & brown spots.;
5. Inhibit excessive production of melanin;

[ Application ]
Can be added to beauty and skin care products, such as brightening cream, brightening foundation, pressed powder, freckle cream (sunburn, freckles)

About Nonapeptide-1 (Melanostatine-5)
Nonapeptide-1 is a biomimetic peptide, which has a very good match with the MC1 receptor on melanocytes, so it can be used as an antagonist of melanocyte-stimulating hormone, competitively binding to the MC1 receptor, can prevent further activation of tyrosinase to produce melanin.
Nonapeptide-1 competitively blocks the receptors on melanoblasts and the entrance of various factor signals, weakens the activity of melanoblasts, reduces the production of melanin, and evens and brightens the skin tone.
Nonapeptide-1 is one skin whitening nonapeptide. It can be applied to various kinds of whitening or spot corrective products.