Chlorobutanol

[ CAS No. ] 57-15-8
[ Molecular Formula ] C4H7Cl3O 
[ Molecular Weight ] 177.47 
[ Appearance ] White crystal
[ Purity ] ＞98.5% 
[ Density ]  1.404g/cm3
[ Boiling Point(°C) ]  167°C at 760 mmHg
[ Flash Point(°C) ]  61.8°C
About Chlorobutanol
Chlorobutanol can be used as a preservative and is often used in ophthalmic preparations, especially for non-aqueous preparations.
Chlorobutanol is primarily used in ophthalmic or parenteral dosage forms as an antimicrobial preservative at concentrations up to 0.5% w/v. It is commonly used as an antibacterial agent for epinephrine solutions, posterior pituitary extract solutions, and ophthalmic preparations intended for the treatment of miosis. It is especially useful as an antibacterial agent in nonaqueous formulations. Chlorobutanol is also used as a preservative in cosmetics; as a plasticizer for cellulose esters and ethers; and has been used therapeutically as a mild sedative and local analgesic in dentistry.