Alanyl-glutamine

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[ Other Name ] L-Alanyl-L-glutamine
[ Cas NO. ] 39537-23-0
[ Molecular Formula ] C8H15N3O4
[ Molecular Weight ] 217.225
[ Appearance ] White Powder
[ Melting Point ] 215 °C
[ Boiling Point ] 615℃

[ Function ]
1. Improve culture medium stability;
2. Inhibit cells from producing harmful ammonia;
3. Improve cell proliferation ability;

[ Application ]
1. As a supplement;
2. As a component in growth medium and incubation medium (IM) for retinal cell lines for experimental treatment of retinal cell lines respectively;

About Alanyl-glutamine
Alanyl-glutamine is a glutamine dipeptide that benefits the antioxidant system, reduces inflammation, and may modulate heat shock protein (HSP) responses in catabolic situations.
Alanyl-glutamine is an essential supplement for cell culture. The free amino acid L-glutamine is unstable and usually degrades to pyroglutamic acid. Ala-Gln and Gly-Gln are used in cell culture as alternative forms of stabilized L-glutamine. The main advantage of using Alanyl-glutamine instead of L-glutamine is that it reduces the level of ammonia produced during cell culture.
Alanyl-glutamine is an alternative supplement to L-glutamine widely used in biopharmaceutical manufacturing. Alanyl-glutamine also acts as an antioxidant (peroxide) and anti-apoptotic (induced by LPS, etc.) factor. Alanyl-glutamine has been used to study injury and sepsis, as well as to study the effects of radiation on leucine and protein metabolism in the body. Alanyl-glutamine has been used to study polymorphonuclear leukocytes and myeloperoxidase activity in vitro.