Apalutamide
[ Synonyms ] ARN-509;4-(7-(6-cyano-5-(trifluoroMethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspirooctan-5-yl)-2-fluoro-N-MethylbenzaMide;AR509;4-[7-[6-Cyano-5-(trifluoromethyl)pyridin-3-yl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl]-2-fluoro-N-methylbenzamide;Benzamide, 4-[7-[6-cyano-5-(trifluoromethyl)-3-pyridinyl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]oct-5-yl]-2-fluoro-N-methyl-;
[ CAS No. ] 956104-40-8
[ Molecular Formula ] C21H15F4N5O2S
[ Molecular Weight ] 477.43500
[ Appearance ] white powder
About Apalutamide
Apalutamide is a selective and competitive androgen receptor inhibitor with IC50 of 16 nM in a cell-free assay, useful for prostate cancer treatment.
Apalutamide is used to treat castration-resistant prostate cancer as it has a good effect on inhibiting the survival and growth of cancer cells.
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