Bivalirudin
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[ CAS No. ] 128270-60-0
[ Molecular Formula ] C98H138N24O33
[ Molecular Weight ] 2180.29
[ Sequence ] D-Phe-Pro-Arg-Pro-Gly-Gly-Gly-Gly-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-OH
[ Purity ] ≥98%
[ Appearance ] White to off-white Powder
[ Uses ] Anticoagulant; antithrombotic.
About Bivalirudin
Bivalirudin is an alternative medicine as ordinary heparin and platelet glycoprotein IIb/IIIa antagonists.
Bivalirudin is a kind of synthetic novel anticoagulants. Bivalirudin directly inhibits thrombin by specifically binding as well to the catalytic site and to the anion-binding exosite of circulating and clot-bound thrombin. Bivalirudin is a specific and reversible direct thrombin inhibitor.
Bivalirudin is a specific and reversible direct thrombin inhibitor (DTI).Chemically, it is a synthetic congener of the naturally occurring drug hirudin (found in the saliva of the medicinal leech Hirudo medicinalis).
Bivalirudin is a DTI which overcomes many limitations seen with indirect thrombin inhibitors, such as heparin.
[ Storage Temp ] -20°C
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