Cecropin B (free acid)

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[ Cas NO. ] 203265-23-0
[ Molecular Formula ] C176H301N51O42S
[ Molecular Weight ] 3835.71
[ Appearance ] White Powder

[ Function ]
1. Antimicrobial activity: Cecropin B has shown broad-spectrum antimicrobial activity against both Gram-positive and Gram-negative bacteria, as well as fungi. It can disrupt the integrity of microbial cell membranes, leading to cell death.
2. Immunomodulation: In addition to its antimicrobial properties, Cecropin B has been found to modulate the immune response. It can stimulate the production of various immune cells and cytokines, which may have implications for immunotherapy and immune system regulation.
3. Anticancer potential: Studies have shown that Cecropin B exhibits cytotoxic effects against cancer cells, including breast cancer, lung cancer, and leukemia cells. It can induce apoptosis (programmed cell death) in cancer cells while having minimal toxicity towards normal cells.

About Cecropin B (free acid)
Cecropin B is a type of antimicrobial peptide (AMP) that is naturally found in insects, particularly in the hemolymph (circulating fluid) of the silkworm (Bombyx mori). It belongs to the family of cecropins, which are cationic peptides known for their antimicrobial activity against a wide range of bacteria, fungi, and even some viruses.Cecropin B has multiple biological activities, including antibacterial, antiviral, antifungal and antitumor effects.
Antimicrobial peptides like Cecropin B are part of the innate immune system of insects and play a crucial role in defending against microbial infections. They are small proteins consisting of 35-39 amino acids and possess a positive charge due to the presence of multiple basic amino acids. The positive charge allows them to interact with the negatively charged microbial cell membranes, leading to membrane disruption and cell death.
It can be used in the development of antimicrobial agents, including the treatment of pathogenic microbial infections and the control of drug-resistant strains. Cecropin B is also being studied for anticancer and antiviral treatments.
Cecropin B has been studied for its potential applications in various fields, including medicine, agriculture, and biotechnology.