Doxercalciferol
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[ Cas NO. ] 54573-75-0
[ Molecular Formula ] C28H44O2
[ Molecular Weight ] 412.658
[ Appearance ] White Powder
[ Purity ] 98%
About Doxercalciferol
Doxercalciferol is a synthetic vitamin D analogue used to treat secondary hyperparathyroidism in patients with chronic kidney disease. It is a vitamin D3 (cholecalciferol) derivative that is more potent than native vitamin D3.
Doxercalciferol is converted to its active form, 1α,25-dihydroxyvitamin D2, in the liver and kidneys. This active metabolite helps regulate calcium and phosphate metabolism.It is approved for the treatment of secondary hyperparathyroidism in patients with stage 3-4 chronic kidney disease and end-stage renal disease on dialysis.
Doxercalciferol helps lower elevated parathyroid hormone (PTH) levels in these patients, which is a common complication of chronic kidney disease.
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