FOXO4-DRI

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[ Sequence ] H-D-Leu-D-Thr-D-Leu-D-Arg-D-Lys-D-Glu-D-Pro-D-Ala-D-Ser-D-Glu-D-Ile-D-Ala-D-Gln-D-Ser-D-Ile-D-Leu-D-Glu-D-Ala-D-Tyr-D-Ser-D-Gln-D-Asn-D-Gly-D-Trp-D-Ala-D-Asn-D-Arg-D-Arg-D-Ser-D-Gly-D-Gly-D-Lys-D-Arg-D-Pro-D-Pro-D-Pro-D-Arg-D-Arg-D-Arg-D-Gln-D-Arg-D-Arg-D-Lys-D-Lys-D-Arg-D-Gly-OH
[ CAS No. ] 2460055-10-9
[ Molecular Formula ] C228H388N86O64
[ Molecular Weight ] 5358.06
[ Purity ] >98%

[ Function ]
1. It can promote senescent cells to enter the apoptosis process, thus greatly improving the side effects of aging and chemotherapy;
2. It can effectively kill senescent cells without affecting non-senescent cells;
3. It plays a role in maintaining the survival of senescent cells and preventing them from apoptosis;
4. It can effectively resist aging induced by chemical toxicity;

About FOXO4-DRI
FOXO4-DRI is a cell-permeable peptide antagonist that blocks the interaction of FOXO4 and p53. Disruption of the p53-FOXO4 interaction causes p53 to be excluded from the nucleus and channeled into mitochondria to induce apoptosis in senescent cells, ultimately eliminating senescent fibroblasts by triggering apoptosis.
FOXO4-DRI is an anti-aging peptide that induces apoptosis in senescent cells.