GLP-1 (7-37)

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[ Other Name ] Glucagon-Like Peptide (GLP) I (7-37)
[ Sequence ]  H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly-OH
[ CAS NO. ] 106612-94-6
[ Molecular Formula ] C151H228N40O47
[ Molecular Weight ] 3355.71
[ Purity ] ≥98%
[ Appearance ] White Powder

About GLP-1 (7-37)
GLP-1 (7-37) is a peptide hormone that plays an important role in regulating blood sugar levels. It is derived from a larger precursor molecule known as proglucagon, which is produced by specialized cells in the pancreas and the intestines.
GLP-1 (7-37) is secreted by intestinal cells in response to the presence of nutrients, particularly carbohydrates, in the digestive tract. Its primary function is to stimulate the release of insulin from pancreatic beta cells, which helps lower blood sugar levels. GLP-1 (7-37) also inhibits the release of glucagon, a hormone that raises blood sugar levels, from pancreatic alpha cells.
In addition to its effects on insulin and glucagon, GLP-1 (7-37) slows down the emptying of the stomach, which helps regulate the rate at which nutrients are absorbed into the bloodstream. It also promotes satiety, or feelings of fullness, which can help control appetite and body weight.
Due to its beneficial effects on blood sugar control and appetite regulation, GLP-1 (7-37) has been a target for the development of medications used in the treatment of type 2 diabetes. These medications, known as GLP-1 receptor agonists, mimic the action of GLP-1 (7-37) in the body and can help improve glycemic control and reduce body weight.