Indolicidin

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[ CAS NO. ] 140896-21-5
[ Molecular Formula ] C100H132N26O13
[ Molecular Weight ] 1906.325 
[ Appearance ] White Powder
[ Purity ] ≥95%

[ Function ]
1. Antimicrobial;
2. Antitumor;
3. Anti-inflammatory;
4. Antiviral;

About Indolicidin
Indolicidin is an antimicrobial peptide isolated from bovine neutrophil cytoplasmic granules. Indolicidin is a class of small molecule polypeptide bioactive substances produced by the host's innate immune defense system to resist infection by external pathogens, and are important effector molecules of innate immunity. 
Indolicidin has the advantages of broad antimicrobial spectrum, thermal stability, and good water solubility, and has become a hot topic of research at home and abroad.
The antibacterial mechanism of indolicidin may be due to increasing the permeability of the cell membrane, allowing itself to enter the bacteria, which can promote the outflow of bacterial contents on the one hand, and on the other hand, it can bind to bacterial DNA and protein macromolecules related to DNA replication, inhibiting DNA replication, thereby playing a bactericidal role.
Indolicidin has a wide antibacterial spectrum and is effective against a variety of Gram-positive and Gram-negative bacteria, including some strains that are resistant to traditional antibiotics. In addition, it has been found to have a certain inhibitory effect on certain fungi and viruses, which further highlights its potential in antimicrobial therapy.
Due to its advantages of high efficiency, broad spectrum and low risk of causing bacterial resistance, Indolicidin has attracted widespread attention in the biomedical field.