Katacalcin

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[ Sequence ]
H-Asp-Met-Ser-Ser-Asp-Leu-Glu-Arg-Asp-His-Arg-Pro-His-Val-Ser-Met-Pro-Gln-Asn-Ala-Asn-OH
[ CAS No. ] 85916-47-8
[ Molecular Formula ] C97H154N34O36S2
[ Molecular Weight ] 2436.63
[ Purity ] > 95% by HPLC

About Katacalcin
Katacalcin is a peptide hormone that is primarily associated with the thyroid gland. It belongs to the calcitonin family of peptides, which also includes calcitonin and calcitonin gene-related peptide (CGRP).
Katacalcin is synthesized and secreted by the parafollicular or C cells of the thyroid gland, which are located between the follicles that produce thyroid hormones such as thyroxine (T4) and triiodothyronine (T3). The release of katacalcin is regulated by calcium levels in the bloodstream. When blood calcium levels increase, the secretion of katacalcin is stimulated.
The exact physiological role of katacalcin is not fully understood, and its functions are still being investigated. However, it has been suggested to have several potential effects on various tissues and organs in the body. Some studies have indicated that katacalcin may play a role in calcium and phosphate homeostasis by reducing the levels of these minerals in the blood. It may also have an impact on bone metabolism by inhibiting bone resorption, which is the breakdown of bone tissue.
Additionally, katacalcin has been found to have vasodilatory effects, meaning it can relax and widen blood vessels, leading to increased blood flow. It has been suggested that katacalcin may be involved in regulating blood pressure and vascular tone.