LL-37 Peptide

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[ CAS NO. ] 154947-66-7
[ Molecular Formula ] C205H340N60O53
[ Molecular Weight ] 4493.26
[ Appearance ] White Powder
[ Purity (HPLC) ] ≥95.0%

[ Function ]
1. Antimicrobial;
2. Antibacterial;
3. Anti-endotoxin effect;
4. Immunomodulatory effect;
5. Regulate the release of immune and inflammatory mediators, induce immune cell differentiation and chemotaxis, induce cell differentiation, release cytokines, neutralize endotoxins and anti-tumor, etc., and enhance the body's ability to resist harmful microorganisms;

About LL-37 Peptide
LL-37 Peptide has antibacterial, antiviral, antimicrobial and antifungal properties and has been shown to reduce inflammation. In addition, research shows that its effect on certain malignancies promotes the formation of blood vessels in certain situations.
As an important member of the natural immune system, LL-37 Peptide has strong antimicrobial activity both in vivo and in vitro, including bacteria, fungi and viruses. It also has a certain selective killing effect on some fungi, viruses, tumor cells and protozoa.
LL-37 Peptide may interact with the phospholipid bilayer through the N-terminus of the polymer, disrupt the arrangement of cell membrane phospholipid molecules, change the permeability of the membrane, affect the structure and function of the cell membrane, and cause a large amount of intracellular substances to extravasate, causing cell death; it also causes cell death by inhibiting intracellular nucleic acid and protein synthesis, enzyme activity and cell wall synthesis.
Compared with traditional antibiotics, LL-37 Peptide can kill pathogens and is not easy to develop drug resistance or immune rejection reactions. It is an important effector molecule of the innate immune system.