Ozagrel

[ CAS No. ]  82571-53-7
[ Molecular Formula ] C13H12N2O2
[ Molecular  Weight ]  228.25
[ Appearance ]  White powder
[ Melting point ]  221~226οC
[ Density ]  1.17g/cm3
[ Boiling point ]   468°C at 760 mmHg
[ Flash point ]  236.8°C
[ Usage ] 
Used in the treatment of acute thrombotic cerebral infarction and with movement disorders.
[ Application ] A potent and selective thromboxane A2 inhibitor
[ Function ] 
1. Used in the treatment of acute thrombotic cerebral infarction and with movement disorders.
2. For Ischemic stroke acute phase.
3. For cerebral vasospasm and the accompanying symptoms of brain ischemia after subarachnoid hemorrhage operation.
About Ozagrel
Ozagrel, an antithrombic drug, is a potent and selective TXA Synthase (thromboxane A2) inhibitor highly active in human platelets. Found to induce apoptosis in T24 and TCC-SUP bladder cancer cells. Ozagrel improved locomotor activity and coordination in ischemia-reperfusion injured mice models and has potential therapeutic usage for stroke. Reported to inhibit pulmonary thromboxane B2 delivery blocking the increase in systemic vascular resistance. Also shown to inhibit phenolase activities of mushroom tyrosinase.