Pasireotide
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[ CAS NO. ] 396091-73-9
[ Molecular Formula ] C58H66N10O9
[ Molecular Weight ] 1047.227
[ Appearance ] White Powder
[ Purity ] 98.9%
[ Function ]
1. It helps reduce the levels of GH in the blood and can lead to the shrinkage of tumors that cause acromegaly. By controlling the excess growth hormone, it helps alleviate symptoms and prevent complications associated with the condition.
2. It inhibits the release of ACTH, thereby reducing the production of cortisol by the adrenal glands.
About Pasireotide
Pasireotide is a medication that belongs to a class of drugs called somatostatin analogs. It is primarily used in the treatment of certain hormone-related conditions, particularly acromegaly and Cushing's disease.
Acromegaly is a rare hormonal disorder characterized by excessive production of growth hormone (GH) by the pituitary gland. This leads to the enlargement of body tissues, such as the hands, feet, and facial features. Pasireotide works by binding to somatostatin receptors on the pituitary gland, which inhibits the release of growth hormone.
Cushing's disease, on the other hand, is a condition caused by excessive production of adrenocorticotropic hormone (ACTH) by a pituitary tumor. This results in the overproduction of cortisol by the adrenal glands, leading to a variety of symptoms such as weight gain, high blood pressure, and diabetes. Pasireotide can help manage Cushing's disease by reducing the secretion of ACTH from the pituitary gland.
Pasireotide is typically administered as an injection under the skin (subcutaneous injection) once or twice a day. It is available in different formulations, including immediate-release and long-acting release. The long-acting release formulation allows for less frequent dosing, which can improve convenience for patients.
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