Pepstatin A
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[ Cas NO. ] 26305-03-3
[ Molecular Formula ] C34H63N5O9
[ Molecular Weight ] 685.89
[ Appearance ] White Powder
[ Purity ] ≥98.0%
About Pepstatin A
Pepstatin A is a naturally occurring protease inhibitor that is commonly used in biological research and applications.
Pepstatin A is a pentapeptide (five amino acids) that was originally isolated from the culture broth of the actinomycete bacteria Streptomyces.
In biological research, pepstatin A is commonly used as an additive to cell lysis and protein extraction buffers to prevent proteolytic degradation of proteins.
It is also used to inhibit the activity of aspartic proteases in studies of protein structure, function, and turnover.
Pepstatin A has potential therapeutic applications, such as in the treatment of high blood pressure (by inhibiting renin) and certain cancers (by inhibiting cathepsin D).
Pepstatin A is a highly selective and potent aspartic protease inhibitor, making it a useful tool in biochemistry and cell biology.
Pepstatin A is widely used in biochemical and biophysical research to study the structure and function of acid proteases. It helps researchers understand the role of these enzymes in cellular processes.
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