Plecanatide

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[ CAS NO. ] 467426-54-6
[ Molecular Formula ] C65H104N18O26S4
[ Molecular Weight ]  1681.89
[ Appearance ] White Powder
[ Purity ] >98.0%

[ Function ]
Can stimulate intestinal secretion of intestinal juice and accelerate defecation

[ Application ]
Indicated for the treatment of chronic idiopathic constipation (CIC) in adults

About Plecanatide
Plecanatide is a medication used in the treatment of chronic idiopathic constipation (CIC) and irritable bowel syndrome with constipation (IBS-C). It is an analog of uroguanylin, a natural hormone that regulates fluid and electrolyte balance in the gastrointestinal tract.
Plecanatide works by activating the guanylate cyclase-C receptor in the lining of the intestines. This activation increases the secretion of chloride and bicarbonate ions into the intestinal lumen, which helps to increase fluid secretion and promote bowel movements. By enhancing fluid secretion and promoting bowel movements, plecanatide can help relieve constipation and improve symptoms associated with CIC and IBS-C.