Pramlintide
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[ Cas NO. ] 151126-32-8
[ Molecular Formula ] C171H267N51O53S2
[ Molecular Weight ] 3949.44
[ Appearance ] White Powder
[ Purity ] 98%
[ Function ]
Pramlintide is used as an adjuvant drug for patients with type 1 and type 2 diabetes.
About Pramlintide
Pramlintide works like a natural substance called balsamol, lowering blood sugar. This drug works by slowing the movement of food through the stomach. It also reduces your appetite and the amount of sugar your liver produces. Pramlintide is not a substitute for insulin, but it may lower the amount of insulin you need.
Pramlintide can reduce the postprandial peak of glucagon secretion in diabetic patients.
Pramlintide is a synthetic analog of amylin, a glucose-regulating hormone that is synthesized by pancreatic beta cells and released into the bloodstream after a meal in a pattern similar to insulin. Like insulin, amylin is deficient in diabetics. It is available as acetate salt. Pramlintide is a 37-amino acid polypeptide that differs structurally from human amylin by substituting proline for alanine, serine, and serine at positions 25, 28, and 29, respectively.
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