Simvastatin
[ CAS No. ] 79902-63-9
[ Synonyms ] (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl 2,2-dimethyl-butanoate
[ Molecular Formula ] C25H38O5
[ Molecular Weight ]418.57
[ Appearance ] White crystal powder
[ Density ] 1.11 g/cm3
[ Melting Point ] 139ºC
[ Boiling Point ] 564.9ºC at 760 mmHg
[ Flash Point ] 184.8ºC
[ Assay ] 98% min (HPLC)
[ Function&Application ]
(1) The primary uses of simvastatin are for the treatment of dyslipidemia and the prevention of cardiovascular disease.
(2) It also can used for the patient with coronary heart disease.
About Simvastatin
To control the blood cholesterol levels and prevent cardiovascular disease.
Simvastatin is a hypolipidemic drug used with exercise, diet, and weight-loss to control elevated cholesterol, or hypercholesterolemia. It is a member of the statin class of pharmaceuticals.
Simvastatin is an HMGCR (HMG-CoA reductase) inhibitor with anti-proliferative properties. This compound has been shown to modulate purified bovine pituitary 20 S proteasome via mild stimulation of chymotrypsin-like activity and inhibition of peptidylglutamylpeptide hydrolyzing activity. Mechanistic studies suggest that Simvastatin decreases CDK4 and CDK2 kinase activities and represses high glucose-induced Rho A (Rho GTPase)/p21 signaling in mesangial cells. Simvastatin also potentiates apoptosis in human myeloid leukemia cells via the suppression of TNF-induced NF-κB activation (IC50 ~ 13 µM).
Note: All pictures & informations are for reference only. The actual goods in kind prevail.
After send online enquiry, we will reply you as soon as possible, if not get any response on time please contact us by Tel or Email.
Welcome to Bolise Co., Ltd.
1. E-mail: [email protected]
2. Tel: +86 592 5365887
Working Time: 8:30--18:00, Monday--Friday
For more information of product, please send the email to [email protected]
- 1. Send Message to US ->
- 2. Confirm Product Information ->
- 3. Order & Payment->
- 4. Packaging&Shipping->
Our products have been certificated with the ISO certificate, free sample is available.
CGMP Manufacturer to ensure the quality stable and reliable.
All of our ingredients meet strict quality and food safety standards, and surpass industry standards for purity and cleanliness.
We are committed to meeting customers' unique needs by providing comprehensive and professional service, enjoying a good reputation among our business partners and customers for high-quality products, excellent after-sales services, competitive prices, and prompt shipping.
Highly welcome friends from all over the world to contact us. We will reply to you as soon as possible, after sending an online inquiry. And please feel free to call us if any urgent inquiry or without getting response from us in time.