Terlipressin

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[ Cas NO. ] 14636-12-5
[ Molecular Formula ] C52H74N16O15S2
[ Molecular Weight ] 1227.38
[ Appearance ] White Powder
[ Purity ] 98%
[ Density ] 1.46±0.1 g/cm3(Predicted)
[ Melting Point ] >170°C (dec.)
[ Boling Point ] 1824.0±65.0 °C(Predicted)
[ Flash Point ] 1056.9°C
[ Solubility ] DMSO (Slightly), Methanol (Slightly)

[ Function ]
1. Hepatorenal Syndrome (HRS): Terlipressin is considered the first-line treatment for type 1 hepatorenal syndrome, a severe complication of advanced liver disease. It acts by increasing systemic vascular resistance, improving renal blood flow, and reducing portal pressure. Terlipressin helps to restore renal function and improve survival rates in patients with HRS.
2. Bleeding Esophageal Varices: Esophageal varices are enlarged veins in the lower part of the esophagus that can rupture and cause life-threatening bleeding in individuals with liver cirrhosis. Terlipressin is used as a vasoconstrictor to control acute bleeding from esophageal varices. By constricting blood vessels, it reduces the blood flow to the varices and minimizes the risk of bleeding.
3. Promote uterine contraction: Terlipressin plays an important role in the delivery process, which can promote uterine contraction and accelerate the delivery process.

About Terlipressin
Terlipressin is a synthetic vasopressin analog that is primarily used for the management of various medical conditions. Its main therapeutic use is in the treatment of hepatorenal syndrome (HRS) and bleeding esophageal varices.In HRS, terlipressin helps to improve renal blood flow and function by constricting blood vessels and reducing portal pressure. This can be beneficial in patients with advanced liver disease who develop kidney dysfunction.