Urolithin B

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[ CAS NO. ] 1139-83-9
[ Molecular Formula ] C13H8O3
[ Molecular Weight ] 212.204
[ Appearance ] White Powder
[ Purity ] ≥98%

[ Function ]
1. Regulate skeletal muscle mass;
2. Anti-Inflammatory effects;
3. Antioxidant properties;
4. Cardiovascular protection;
5. Anti-Cancer;
6. Reduce renal fibrosis and inflammation in animal models of kidney obstruction and alleviating cartilage damage in osteoarthritis;

About Urolithin B
Urolithin B is a natural compound produced by gut bacteria from ellagitannins and ellagic acid, found in foods like pomegranates, raspberries, and walnuts. Research suggests it offers several health benefits, primarily due to its antioxidant and anti-inflammatory properties. 
Urolithin B may promote muscle growth and reduce muscle atrophy by increasing protein synthesis and inhibiting protein breakdown pathways. Studies in animal models show it enhances skeletal muscle mass and strength, potentially aiding conditions like age-related muscle loss.
It suppresses inflammatory pathways (e.g., NF-κB, JNK, ERK, Akt) and reduces pro-inflammatory markers like TNF-α and IL-6, which could help manage chronic inflammation in conditions like osteoarthritis and kidney disease.
Urolithin B counters oxidative stress by reducing reactive oxygen species (ROS) and boosting superoxide dismutase activity, potentially protecting cells from damage in conditions like cardiovascular disease and neurodegeneration. However, its antioxidant capacity may vary compared to other urolithins.
It may prevent hyperlipidemia and protect against heart damage, as shown in studies where it reduced myocardial injury in animal models of ischemia/reperfusion through pathways like p62/Keap1/Nrf2.
Preliminary research indicates Urolithin B inhibits tumor growth in models of leukemia and liver cancer by promoting apoptosis and altering cancer cell metabolism, though human studies are lacking.